Analysis of the thrombosis in blood samples with various concentration of red blood cells using electrical resistance tomography

A. Sapkotaa, Y. Asakuraa, T. Fusea, O. Maruyamab, R. Kosakab, T. Yamanec,

M. Takeia

aDivision of Artificial Systems Science, Graduate School of Engineering, Chiba University, Chiba 2648522 Japan bNational Institute of AIST, Institute of Human Science and Biomedical Engineering, Tsukuba, 3058564 Japan cDepartment of Mechanical Engineering, Graduate School of Engineering, Kobe University, Kobe, 6578501 Japan

Abstract

In this paper, we present an application of electrical resistance tomography to analyze the formation of thrombosis in blood. Experiments were conducted using bovine blood under thrombogenic conditions. The concentration of red blood cells in the blood was varied to see the cell concentration dependent detection of thrombogenic process. The initial changes in thrombogenic conditions, which are due to change in plasma proteins, were noticed in cell- free condition. But, it was difficult to notice the changes caused by plasma proteinsin the presence of natural level of cell concentration

Keywords: image processing; Thrombosis; Electrical Resistance Tomography;Blood Impedance; Multiphase Flow