International Society for Industrial Process Tomography

Influence of Primary Hepatocellular Carcinoma Size and Stage
on Echo Signal in Human Abdomen

Dandan Guo, Shangjie Ren, Feng Dong*

Tianjin Key Laboratory of Process Measurement and Control

School of Electrical and Information Engineering, Tianjin University, Tianjin, China

*Email: fdong@tju.edu.cn

ABSTRACT

Ultrasonic reflections occur at the interface where the acoustic impedance changes when the ultrasonic wave propagates, because different tissues have different acoustic characteristics. Ultrasound reflecting imaging is based on time information and amplitude information in the echo signal. The lesions on the path which is perpendicular to the transmitter and passes though the midpoint of the transmitter were the objects. The lesion position has a one-to-one correspondence with the ToFs in the echo signal. Because the lesions have different acoustic properties at different stages, the amplitude of the echo signal is related to the stage of the lesion. Based on the real human model, primary hepatocellular carcinoma (HCC) was selected as the study disease. Diameters of 4mm, 8mm, 12mm, and 16mm, with a sound speed of 1600m/s, and a diameter of 4mm with sound speed at 1600m/s, 1610m/s, 1620m/s, 1630m/s lesions were simulated respectively The results showed that the extraction of ToFs can reflect the location information of lesions well, and the lesions at different stages could be better differentiated by the amplitude of acoustic waves in echo signals.

Keywords abdomen; hepatocellular carcinoma; primary(HCC); ultrasonic reflection; time of flight

Industrial Application Biomedical Engineering